EdenteV2, Pmc, Curation, bibRecord, 002402

Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study

Identifieur interne : 002402 ( Pmc/Curation ); précédent : 002401; suivant : 002403

Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study

Auteurs : Mainak Kanti Saha ; Prerna Agrawal ; Suparna Ganguly Saha ; Vinod Vishwanathan ; Vandana Pathak ; Sakuru Venkata Saiprasad ; Purvi Dhariwal ; Mahendra Dave

Source :

Journal of Clinical and Diagnostic Research : JCDR [ 2249-782X ] ; 2017.

RBID : PMC:5427438

Abstract

Introduction

Fixed and/or removable prosthodontics caters to the restorative needs of the largest count of geriatric patients whose rehabilitative procedures depend on the quality and quantity of available bone. The common diagnostic parameters for quantifying bone may involve an invasive blood examination, an expensive bone densitometry procedure or a urine analysis. Sialometry involving the basic biochemistry of saliva analysis may be proposed as an alternative to the conventional investigative protocol and its usefulness may be attributed owing to its non invasive and simpler procedure.

Aim

The aim of this study was to compare the salivary calcium and alkaline phosphatase among osteoporotic, osteopenic and normal edentulous subjects.

Materials and Methods

A prospective, comparative and observational study was carried out on 80 selected edentulous subjects (40 males and 40 females) aged 55-75 years (30 osteoporotic, 30 osteopenic and 20 control). A sample of saliva was taken for the study. Salivary calcium was measured by Arsenazo reaction; and alkaline phosphatase by the International Federation of Clinical Chemistry (IFCC) method. Statistical analysis was done by unpaired t-test. A comparison was made in the levels of salivary calcium and alkaline phosphatase with that of osteoporosis and osteopenia.

Results

The mean salivary calcium and alkaline phosphatase levels were found to be significantly higher in the osteoporotic and osteopenic edentulous subjects as compared to the control group.

Conclusion

Salivary calcium and alkaline phosphatase are increased significantly in case of osteoporosis and osteopenia. Hence, screening of salivary samples of patients may be an effective indicator for the detection of underlying disorders of bone metabolism.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427438

DOI: 10.7860/JCDR/2017/24960.9583
PubMed: 28511512
PubMed Central: 5427438

Links toward previous steps (curation, corpus...)

to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002402

Links to Exploration step

PMC:5427438

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study</title>
<author><name sortKey="Saha, Mainak Kanti" sort="Saha, Mainak Kanti" uniqKey="Saha M" first="Mainak Kanti" last="Saha">Mainak Kanti Saha</name>
<affiliation><nlm:aff id="aff1"> Professor and Head, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Agrawal, Prerna" sort="Agrawal, Prerna" uniqKey="Agrawal P" first="Prerna" last="Agrawal">Prerna Agrawal</name>
<affiliation><nlm:aff id="aff2"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Pithampur, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Saha, Suparna Ganguly" sort="Saha, Suparna Ganguly" uniqKey="Saha S" first="Suparna Ganguly" last="Saha">Suparna Ganguly Saha</name>
<affiliation><nlm:aff id="aff3"> Professor and Head, Department of Conservative Dentistry,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Vishwanathan, Vinod" sort="Vishwanathan, Vinod" uniqKey="Vishwanathan V" first="Vinod" last="Vishwanathan">Vinod Vishwanathan</name>
<affiliation><nlm:aff id="aff4"> Reader, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pathak, Vandana" sort="Pathak, Vandana" uniqKey="Pathak V" first="Vandana" last="Pathak">Vandana Pathak</name>
<affiliation><nlm:aff id="aff5"> Senior Lecturer, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Saiprasad, Sakuru Venkata" sort="Saiprasad, Sakuru Venkata" uniqKey="Saiprasad S" first="Sakuru Venkata" last="Saiprasad">Sakuru Venkata Saiprasad</name>
<affiliation><nlm:aff id="aff6"> Principal Scientist, Indian Council of Agricultural Research,<institution>Indian Agricultural Research Institute</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dhariwal, Purvi" sort="Dhariwal, Purvi" uniqKey="Dhariwal P" first="Purvi" last="Dhariwal">Purvi Dhariwal</name>
<affiliation><nlm:aff id="aff7"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dave, Mahendra" sort="Dave, Mahendra" uniqKey="Dave M" first="Mahendra" last="Dave">Mahendra Dave</name>
<affiliation><nlm:aff id="aff8"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">28511512</idno>
<idno type="pmc">5427438</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427438</idno>
<idno type="RBID">PMC:5427438</idno>
<idno type="doi">10.7860/JCDR/2017/24960.9583</idno>
<date when="2017">2017</date>
<idno type="wicri:Area/Pmc/Corpus">002402</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002402</idno>
<idno type="wicri:Area/Pmc/Curation">002402</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002402</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study</title>
<author><name sortKey="Saha, Mainak Kanti" sort="Saha, Mainak Kanti" uniqKey="Saha M" first="Mainak Kanti" last="Saha">Mainak Kanti Saha</name>
<affiliation><nlm:aff id="aff1"> Professor and Head, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Agrawal, Prerna" sort="Agrawal, Prerna" uniqKey="Agrawal P" first="Prerna" last="Agrawal">Prerna Agrawal</name>
<affiliation><nlm:aff id="aff2"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Pithampur, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Saha, Suparna Ganguly" sort="Saha, Suparna Ganguly" uniqKey="Saha S" first="Suparna Ganguly" last="Saha">Suparna Ganguly Saha</name>
<affiliation><nlm:aff id="aff3"> Professor and Head, Department of Conservative Dentistry,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Vishwanathan, Vinod" sort="Vishwanathan, Vinod" uniqKey="Vishwanathan V" first="Vinod" last="Vishwanathan">Vinod Vishwanathan</name>
<affiliation><nlm:aff id="aff4"> Reader, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pathak, Vandana" sort="Pathak, Vandana" uniqKey="Pathak V" first="Vandana" last="Pathak">Vandana Pathak</name>
<affiliation><nlm:aff id="aff5"> Senior Lecturer, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Saiprasad, Sakuru Venkata" sort="Saiprasad, Sakuru Venkata" uniqKey="Saiprasad S" first="Sakuru Venkata" last="Saiprasad">Sakuru Venkata Saiprasad</name>
<affiliation><nlm:aff id="aff6"> Principal Scientist, Indian Council of Agricultural Research,<institution>Indian Agricultural Research Institute</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dhariwal, Purvi" sort="Dhariwal, Purvi" uniqKey="Dhariwal P" first="Purvi" last="Dhariwal">Purvi Dhariwal</name>
<affiliation><nlm:aff id="aff7"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dave, Mahendra" sort="Dave, Mahendra" uniqKey="Dave M" first="Mahendra" last="Dave">Mahendra Dave</name>
<affiliation><nlm:aff id="aff8"> Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Clinical and Diagnostic Research : JCDR</title>
<idno type="ISSN">2249-782X</idno>
<idno type="eISSN">0973-709X</idno>
<imprint><date when="2017">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Introduction</title>
<p>Fixed and/or removable prosthodontics caters to the restorative needs of the largest count of geriatric patients whose rehabilitative procedures depend on the quality and quantity of available bone. The common diagnostic parameters for quantifying bone may involve an invasive blood examination, an expensive bone densitometry procedure or a urine analysis. Sialometry involving the basic biochemistry of saliva analysis may be proposed as an alternative to the conventional investigative protocol and its usefulness may be attributed owing to its non invasive and simpler procedure.</p>
</sec>
<sec><title>Aim</title>
<p>The aim of this study was to compare the salivary calcium and alkaline phosphatase among osteoporotic, osteopenic and normal edentulous subjects.</p>
</sec>
<sec><title>Materials and Methods</title>
<p>A prospective, comparative and observational study was carried out on 80 selected edentulous subjects (40 males and 40 females) aged 55-75 years (30 osteoporotic, 30 osteopenic and 20 control). A sample of saliva was taken for the study. Salivary calcium was measured by Arsenazo reaction; and alkaline phosphatase by the International Federation of Clinical Chemistry (IFCC) method. Statistical analysis was done by unpaired t-test. A comparison was made in the levels of salivary calcium and alkaline phosphatase with that of osteoporosis and osteopenia.</p>
</sec>
<sec><title>Results</title>
<p>The mean salivary calcium and alkaline phosphatase levels were found to be significantly higher in the osteoporotic and osteopenic edentulous subjects as compared to the control group.</p>
</sec>
<sec><title>Conclusion</title>
<p>Salivary calcium and alkaline phosphatase are increased significantly in case of osteoporosis and osteopenia. Hence, screening of salivary samples of patients may be an effective indicator for the detection of underlying disorders of bone metabolism.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <front><journal-meta><journal-id journal-id-type="nlm-ta">J Clin Diagn Res</journal-id>
<journal-id journal-id-type="iso-abbrev">J Clin Diagn Res</journal-id>
<journal-id journal-id-type="hwp">Journal of Clinical and Diagnostic Research</journal-id>
<journal-id journal-id-type="publisher-id">JCDR</journal-id>
<journal-title-group><journal-title>Journal of Clinical and Diagnostic Research : JCDR</journal-title>
</journal-title-group>
<issn pub-type="ppub">2249-782X</issn>
<issn pub-type="epub">0973-709X</issn>
<publisher><publisher-name>JCDR Research and Publications (P) Limited</publisher-name>
<publisher-loc>Delhi, India</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">28511512</article-id>
<article-id pub-id-type="pmc">5427438</article-id>
<article-id pub-id-type="doi">10.7860/JCDR/2017/24960.9583</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Dentistry Section</subject>
<subj-group subj-group-type="heading"><subject>Original Article</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group><article-title>Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Saha</surname>
<given-names>Mainak Kanti</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Agrawal</surname>
<given-names>Prerna</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Saha</surname>
<given-names>Suparna Ganguly</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Vishwanathan</surname>
<given-names>Vinod</given-names>
</name>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pathak</surname>
<given-names>Vandana</given-names>
</name>
<xref ref-type="aff" rid="aff5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Saiprasad</surname>
<given-names>Sakuru Venkata</given-names>
</name>
<xref ref-type="aff" rid="aff6">6</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dhariwal</surname>
<given-names>Purvi</given-names>
</name>
<xref ref-type="aff" rid="aff7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dave</surname>
<given-names>Mahendra</given-names>
</name>
<xref ref-type="aff" rid="aff8">8</xref>
</contrib>
</contrib-group>
<aff id="aff1"><label>1</label>
 Professor and Head, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</aff>
<aff id="aff2"><label>2</label>
 Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Pithampur, Madhya Pradesh, India</addr-line>
.</aff>
<aff id="aff3"><label>3</label>
 Professor and Head, Department of Conservative Dentistry,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</aff>
<aff id="aff4"><label>4</label>
 Reader, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</aff>
<aff id="aff5"><label>5</label>
 Senior Lecturer, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</aff>
<aff id="aff6"><label>6</label>
 Principal Scientist, Indian Council of Agricultural Research,<institution>Indian Agricultural Research Institute</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</aff>
<aff id="aff7"><label>7</label>
 Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</aff>
<aff id="aff8"><label>8</label>
 Postgraduate Student, Department of Prosthodontics,<institution>College of Dental Science and Hospital</institution>
,<addr-line>Indore, Madhya Pradesh, India</addr-line>
.</aff>
<author-notes><corresp id="cor1">NAME, ADDRESS, E-MAIL ID OF THE CORRESPONDING AUTHOR: Dr. Prerna Agrawal, Malwa Hospital and Research Center, Sector-1, Pithampur-452005, Madhya Pradesh, India. E-mail: <email>prerna.agrawal03@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>3</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub"><day>01</day>
<month>3</month>
<year>2017</year>
</pub-date>
<volume>11</volume>
<issue>3</issue>
<fpage>ZC63</fpage>
<lpage>ZC66</lpage>
<history><date date-type="received"><day>23</day>
<month>10</month>
<year>2016</year>
</date>
<date date-type="rev-request"><day>09</day>
<month>12</month>
<year>2016</year>
</date>
<date date-type="accepted"><day>30</day>
<month>1</month>
<year>2017</year>
</date>
</history>
<permissions><copyright-statement>© 2017 Journal of Clinical and Diagnostic Research</copyright-statement>
<copyright-year>2017</copyright-year>
</permissions>
<abstract><sec><title>Introduction</title>
<p>Fixed and/or removable prosthodontics caters to the restorative needs of the largest count of geriatric patients whose rehabilitative procedures depend on the quality and quantity of available bone. The common diagnostic parameters for quantifying bone may involve an invasive blood examination, an expensive bone densitometry procedure or a urine analysis. Sialometry involving the basic biochemistry of saliva analysis may be proposed as an alternative to the conventional investigative protocol and its usefulness may be attributed owing to its non invasive and simpler procedure.</p>
</sec>
<sec><title>Aim</title>
<p>The aim of this study was to compare the salivary calcium and alkaline phosphatase among osteoporotic, osteopenic and normal edentulous subjects.</p>
</sec>
<sec><title>Materials and Methods</title>
<p>A prospective, comparative and observational study was carried out on 80 selected edentulous subjects (40 males and 40 females) aged 55-75 years (30 osteoporotic, 30 osteopenic and 20 control). A sample of saliva was taken for the study. Salivary calcium was measured by Arsenazo reaction; and alkaline phosphatase by the International Federation of Clinical Chemistry (IFCC) method. Statistical analysis was done by unpaired t-test. A comparison was made in the levels of salivary calcium and alkaline phosphatase with that of osteoporosis and osteopenia.</p>
</sec>
<sec><title>Results</title>
<p>The mean salivary calcium and alkaline phosphatase levels were found to be significantly higher in the osteoporotic and osteopenic edentulous subjects as compared to the control group.</p>
</sec>
<sec><title>Conclusion</title>
<p>Salivary calcium and alkaline phosphatase are increased significantly in case of osteoporosis and osteopenia. Hence, screening of salivary samples of patients may be an effective indicator for the detection of underlying disorders of bone metabolism.</p>
</sec>
</abstract>
<kwd-group><kwd>Edentulous patient</kwd>
<kwd>Osteoporotic patients</kwd>
<kwd>Salivary analysis</kwd>
<kwd>Screening</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Pmc/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002402 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 002402 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    EdenteV2
   |flux=    Pmc
   |étape=   Curation
   |type=    RBID
   |clé=     PMC:5427438
   |texte=   Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i   -Sk "pubmed:28511512" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a EdenteV2

This area was generated with Dilib version V0.6.32.
Data generation: Thu Nov 30 15:26:48 2017. Site generation: Tue Mar 8 16:36:20 2022

	Serveur d'exploration sur le patient édenté
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le patient édenté

Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study

Evaluation of Correlation between Salivary Calcium, Alkaline Phosphatase and Osteoporosis- A Prospective, Comparative and Observational Study

Source :

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki